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Nanobiotechnology

Nanobiotechnology

INTRODUCTION:

Nanotechnology is science, engineering, and technology conducted at the nanoscale, which is about 1 to 100 nanometers.

NANOPARTICLES:

A nanoparticle is a small object that behaves as a whole unit in terms of its transport and properties.

SIZE OF NANOPARTICLES:

In terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles are sized between 1 and 100 nanometers. Nanoparticles may or may not exhibit size-related properties that are seen in fine particles. Despite being the size of the ultrafine particles individual molecules are usually not referred to as nanoparticles.

Nanoclusters have at least one dimension between 1 and 10 nanometers and a narrow size distribution. Nano powders on the other hand are agglomerates of ultrafine particles, nanoparticles, or nanoclusters. Nano particle sized crystals are called nanocrystals.

Nanobiotechnology

Uses and Advantages of Nanoparticles:

Some of the uses of nanoparticles in biology and medicine include:

  • Creating fluorescent biological labels for important biological markers and molecules in research and diagnosis of diseases
  • Drug delivery systems
  • Gene delivery systems in gene therapy
  • For biological detection of disease causing organisms and diagnosis
  • Detection of proteins
  • Isolation and purification of biological molecules and cells in research
  • Probing of DNA structure
  • Genetic and tissue engineering
  • Destruction of tumours with drugs or heat
  • In MRI studies
  • In pharmacokinetic studies.

How Nanoparticles Are Formed ?

There are several methods for creating nanoparticles, including gas condensation, attrition, chemical precipitation, ion implantation Ion implantation-induced nanoparticle formation, pyrolysis and hydrothermal synthesis. In attrition, macro- or micro-scale particles are ground in a ball mill, a planetary ball mill, or other size-reducing mechanism. The resulting particles are air classified to recover nanoparticles. In pyrolysis, a vaporous precursor (liquid or gas) is forced through an orifice at high pressure and burned. The resulting solid (a version of soot) is air classified to recover oxide particles from by-product gases. Traditional pyrolysis often results in aggregates and agglomerates rather than single primary particles. Ultrasonic nozzle spray pyrolysis (USP) on the other hand aids in preventing agglomerates from forming.

Selenium Nanoparticles:

Se nanoparticles have strong absorption around 565 nm. They have bright red color, thus can be used as biological sample staining reagent with permanent color.  In addition, Se nanoparticles have shown strong anti-cancer effect both in vitro and in vivo. Compared with Se element, Nanostructured Se showed less toxicity tested both in vitro and in vivo. Nanocs now provides functional selenium (Se) nanoparticles for biomedical research. We can also provides other Se nanoparticle based products based on customer request. 

Nanobiotechnology

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